Resistance Versus Aerobic Exercise: Acute effects on glycemia in type 1 diabetes

Jane E.Yardley1,2, Glen P. Kenny1,2, Bruce A. Perkins3, Michael C. Riddell4, Nadia Balaa1, Janine Malcolm5,6, Pierre Boulay7, Farah Khandwala8, Ronald J. Sigal6,8,9

1. Human and Environmental Physiology Research Unit, University of Ottawa, Ottawa, Ontario, Canada;
2. Institute of Population Health, University of Ottawa, Ottawa, Ontario, Canada;
3. University Health Network, Toronto General Hospital, Toronto, Ontario, Canada;
4. School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada;
5. Faculty of Medicine, University of Ottawa,Ottawa, Ontario, Canada;
6. Ottawa Hospital Research Institute, Ottawa, Ontario, Canada;
7. Champlain Diabetes Regional Coordination Centre, Ottawa, Ontario, Canada;
8. Alberta Health Services, Calgary, Alberta, Canada;
9. Departments of Medicine, Cardiac Sciences, and Community Health Sciences, Faculties of Medicine and Kinesiology, University of Calgary, Calgary, Alberta, Canada.

OBJECTIVE

In type 1 diabetes, small studies have found that resistance exercise (weight lifting) reduces HbA1c. In the current study, we examined the acute impacts of resistance exercise on glycemia during exercise and in the subsequent 24 h compared with aerobic exercise and no exercise.

RESEARCH DESIGN AND METHODS

Twelve physically active individuals with type 1 diabetes (HbA1c 7.1 6 1.0%) performed 45 min of resistance exercise (three sets of sevenexercises at eight repetitions maximum), 45 min of aerobic exercise (running at 60% of VO2max), or no exercise on separate days. Plasma glucose was measured during and for 60 min after exercise. Interstitial glucose was measured by continuous glucose monitoring 24 h before, during, and 24 h after exercise.

RESULTS

Treatment-by-time interactions (P , 0.001) were found for changes in plasma glucose during and after exercise. Plasma glucose decreased from 8.462.7 to 6.862.3mmol/L (P = 0.008) during resistance exercise and from9.263.4 to 5.862.0mmol/L (P = 0.001) during aerobic exercise.No significant changes were seen during the no-exercise control session. During recovery, glucose levels did not change significantly after resistance exercise but increased by 2.2 6 0.6 mmol/L (P = 0.023) after aerobic exercise. Mean interstitial glucose from 4.5 to 6.0 h postexercise was significantly lower after resistance exercise versus aerobic exercise.

CONCLUSIONS

Resistance exercise causes less initial decline in blood glucose during the activity but is associated with more prolonged reductions in postexercise glycemia than aerobic exercise. This might account for HbA1c reductions found in studies of resistance exercise but not aerobic exercise in type 1 diabetes.

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